A 75-year-old man is brought in to your office by his wife. She complains that he is not the same over the last 6 months. His memory is failing him, he has difficulty walking (especially when he initiates walking), and he is incontinent of urine. Which of the following is the most likely diagnosis based on his history?
Answer: Normal-pressure hydrocephalus (NPH)
Discussion: Normal-pressure hydrocephalus(NPH) is a cause of dementia in the elderly. It may be
caused by previous insult to the brain, usually as a result of a subarachnoid hemorrhage or diffuse meningitis that presumably results in scarring of the arachnoid villi over the brain convexities where cerebrospinal fluid (CSF) absorption usually occurs. However, elderly NPH patients seldom have a
history of predisposing disease.
NPH classically consists of
- dementia,
- apraxia of gait, and
- incontinence





