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Thursday, November 24, 2016

Actinic keratoses - Brief Discussion



Actinic, or solar, keratoses (AK) is a rough, scaly patch on the skin and is a common premalignant lesion that develops as a consequence of chronic sun exposure.  It's most commonly found on your face, lips, ears, back of your hands, forearms, scalp or neck.

Clinical Features: 

  • small, crusty or scaly, lesions
  • may be pink, red, brown or the same color as the skin
  • typically on sun exposed areas e.g. temples of head
  • multiple lesions may be present
It can be difficult to distinguish between noncancerous spots and cancerous ones. So it's best to have new skin changes evaluated by a doctor — especially if a spot or lesion persists, grows or bleeds.

Risk Factors: include:
  • Age older than 40
  • Living in a sunny climate
  • A history of frequent or intense sun exposure or sunburn
  • Red or blond hair, and blue or light-colored eyes
  • People who tend to freckle or burn when exposed to sunlight
  • Have a personal history of an actinic keratosis or skin cancer
  • Have a weak immune system as a result of chemotherapy, leukemia, AIDS or organ transplant medication
Diagnosis is clinical on the basis of history and examination. If there is any doubt a skin biopsy can be done.

Management: options include
  • prevention of further risk: e.g. sun avoidance, sun cream
  • fluorouracil cream: typically a 2 to 3 week course. The skin can become red and inflamed sometimes
  • topical hydrocortisone is given following fluorouracil to help settle the inflammation
  • topical diclofenac: may be used for mild AKs. Moderate efficacy but much fewer side effects
  • topical imiquimod: trials have shown good efficacy
  • cryotherapy
  • curettage and cautery

2 comments:


  1. I feel so excited today because it's just a year since I got my breakthrough from Herpes.I was diagnosed of HSV1 on the 12/4/2015 and latter i got affected with the HSV2. That was my 2nd outbreak after i lost my ex fiance that got me affected with the virus. I was so scared when he died and what i heard about the Herpes virus as he's deathly and such has no cure. I feel so pity and and a disgrace to my personality,in my career and my family to have been in with the deathly sickness, and that would makes my love ones siblings stay far from me. I was going to my regular church activities when i begin to hear testimonies of how people get cure online, i never gave it a thought till my cousin Stephanie who was affected with HIV told me, Lenny you need not to worry cos i met i man today online , i traditional herbal healer whom two of her friends confirmed he cure them with his herbal herbs that i should give it a try. I saw the interest in her and she did contact the herbal doctor again in my present, luckily for me he picked and show up himself, behold he was at about to attain to some patients that have came back with appreciation of how he cure them from Cancer, HIV, and off much too the herpes he cured an 18 years old daughter.
    I was so happy that day, i wanted to be there but the distance was a barrier to me. I told him how the virus had eaten me up and and a truly believe there's cure for herpes. He told me me with assurance that my case wont be different and he had been curing lots of people With his herbal medicine and most people due contact him from the States and preperd the medicine and made use of the DHL to reach him.
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    He made me do away with the medical prescription,the acyclovir (Zovirax), famciclovir(Famvir), and valacyclovir (valtrex). you don't know him because you haven't meet this man try and contact him yourself Dr. Akpu in Africa is popularly known in his City,and you can request for his address yourself. I'm so happy now cos,I and my cousin had been confirmed negative till date..the Lord is good in my life. Dr. Akpu sent me his herbal medicine that heal me too, 🙏 🙏 Dr. Akpu for giving me another life.
    Contact Dr.akpu for all kids of sickness@
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  2. I was diagnosed of herpes virus, I have tried all possible means to get cure but all my effort proved abortive, until a friend of mine introduced me to a herbal doctor called Dr Agaba, who prepare herbal medicine to cure all kind of diseases including herpes virus (Herpes), when i contacted this herbal doctor via email, he sent me herpes virus herbal medicine via courier service, when i received the herbal medicine he gave me step by step instructions on how to apply it, when i applied it as instructed i was totally cured from the virus within 3 weeks of usage. Contact this great herbal doctor today to get your cure. 
    Via Email: Dragabasolutionhome@gmail.com or WhatApp: +2349074536486    

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