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Monday, July 13, 2015

A 15-Year Old Female With Right Upper Quadrant Abdominal Pain.

A 15-year-old Nigerian female was admitted with right upper quadrant abdominal pain. She had a history of sickle cell anemia, and had several admissions with hand and foot crises. During the last two admissions she complained of abdominal pain. She was born in England. She was the only child of a middle-class family.
On examination, she was distressed with pain. The temperature was 37.6°C (99.7°F). She was mildly jaundiced. The pulse was 105 beats/min, and blood pressure 100/75 mmHg. On examination of the respiratory system there was dullness to percussion on the anterior aspect of the right lung. Abdominal examination revealed tenderness in the right upper quadrant. The liver was palpable 3 cm below the costal margin.
Investigations are shown.


  • Hb 6 g/dl
  • WCC 12 109/l
  • Platelets 200 109/l
  • U&E Normal
  • AST 50 iu/l
  • Alkaline phosphatase 150 iu/l
  • Albumin 34 g/l
  • Urine osmolality 120 mOsm/kg
  • Urinalysis Urobilinogen +++, Blood 0, Protein 0 ,Bilirubin 0
  • Chest X-ray Opacification in the right upper zone


Practice Questions with Answers:

1. What is the cause of the abdominal pain?

Acute cholecystitis.
 The story is typical of cholecystitis which, in this case, is secondary to pigment gallstones. Hepatic infarction due to a sickling crisis in the liver is unlikely because it would be associated with a higher AST. Sequestration is unlikely because it is very rare in older patients with sickle cell anemia.

2. What investigation would you request next?
Ultrasound examination of the liver.

3. What is the cause of the girl’s respiratory and chest X-ray findings?
The shadowing on the chest X-ray is probably secondary to streptococcal pneumonia. Patients with sickle cell anaemia are hyposplenic as a result of autosplenic infarction. As a result, they are predisposed to bacterial infections by capsulated organisms such as Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae. Pulmonary infarction may also cause pulmonary shadowing on the chest X-ray – but is less likely in the absence of pleurisy – and severe breathlessness.

2 comments:

  1. Hello, my name is Betty. i was diagnosed of HIV virus 4 years back. Before then, i was dating this Derrick guy. we had something great going on. Our love life only lasted for 8 months. the sixth and seven month of our relationship, i began feeling very weak every now and then. But i never suspected anything until I kept on experiencing different symptoms like having sore throats, constant headache, body weakness e.t.c. I decided to go for a medical check up. I was tested HIV positive. when the doctor broke the news to me, it was as if my whole world had crumbled. it dawned on me then that Derrick has been lying to me. i was very mad to an extent i almost committed suicide. But there was nothing i could do, other than weep and weep. ever since then, i have been spending heavily on medications, going from one medical clinic or the other so I can look healthy. Though since i was a kid, i love herbs a lot. i take herbal tea with grandma while growing so i am quite familiar with herbs. early last year, i was on the internet and on a particular health blog, to check for herbal medication as alternative. I saw many comments and read many testimonies. Until i came across a particular testimony on how Dr.ugo cured a patient from herpes simplex virus using pure natural herbs. i reached out to the doctor because I also was thinking Herpes had no cure. I told him about my HIV status.He encouraged me not to panic that he will help me get my deliverance. he prepared some herbs and sent them to me. The herbs were in four 70ml bottles and I took them morning and night. i used as he directed, and in less than three weeks, i started having appetite to eat plenty of food and i gained back my strength. the fourth week,I consumed all the herbal meds. He encouraged me to go for a test which i did. This time, the result was negative. I quickly contacted the doctor and informed him of the news. I immediately asked him to prepare for Derrick too. He did and sent it. Today, me and Derrick are HIV free. All thanks goes to God Almighty for healing us through Dr.Ugo. if you are having any kind of sickness at all, Dr.Ugo is the right person to talk to and i assure you, you will be glad you did. His email: ugoherbalhome@gmail.com you can also write him on WhatsApp +2348104990619.

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  2. Nice blog
    Have been totally convinced that HIV,and many others dangerous diseases can be best cured using the Herbal Medicine. Dr.Akpu the great and powerful herbalist cured me with his Herbal remedy. I'm Linda,15 years from Texas. I was born with HIV. I lost parents at my teenager age when I was 4th. I had to grew up with my mum only Sister, whom I loved so much. She was so worried about my life as my condition was her mature problem in life. I had taken lots of antiviral treatment to get ride of the virus not believing what there said HIV has no cure. I was on the internet when i came across blogs of testimony about a lady who where cured of a 7 years diagnose of Herpes by this powerful Herbalist, Dr.Akpu.I wrote down his mail @ Dr.akpupowerherbscenter@gmail.com
    I told my Aunt,luckily it was the same Dr,we where referred to few months back by my pastor in church whom members have being testifying about of his cure We did contacted him and explained my problem to him.He prepared the medicine and sent to me with details of how to use and apply. After a while, I began to feel more strong than never before, I felt so lucky and happy when my Doctor congratulated me that he could found no HIV virus again in me. I knew I was free cos my body was so strong. His herbal medicine should have saved my parents life, i said!
    Thanks so much for reading my article, you should share your testimony if you have cure as well
    Dr.akpupowerherbscenter@gmail.com
    Is the solution

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